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The Second COVID-19 Shot Is a Rude Reawakening for Immune Cells

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Side effects are a natural part of the vaccination process. Not everyone will experience them. But the two COVID-19 vaccines cleared for emergency use in the United States, made by Pfizer/BioNTech and Moderna, already have reputations for raising the hackles of the immune system: In both companies’ clinical trials, at least a third of the volunteers ended up with symptoms such as headaches and fatigue, but these are just a sign that protection is kicking in as it should. Read more about how vaccines work here.

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