Should someone who has had GBS unrelated to COVID-19 vaccination have a COVID-19 vaccination?
Yes, they should be vaccinated as recommended for their age and risk group.
A causal link between COVID-19 vaccination and GBS has not been proven and there is no evidence of a higher rate of reporting of GBS following COVID-19 vaccination in individuals who have previously had GBS. Hence, the balance of risk benefit is in favour of having a full COVID-19 vaccination schedule.
If someone has had GBS after their first COVID-19 vaccination, should they have a second dose?
Yes, they should complete the vaccination schedule with the same COVID-19 vaccine.
There is no evidence that a previous episode of GBS predisposes an individual to further episodes. Hence, in those who develop GBS following COVID-19 vaccination, the balance of risk benefit is still in favour of completing a full COVID-19 vaccination schedule. In addition, a causal link between COVID-19 vaccination and GBS has not been proven and cases of GBS that occur following vaccination may occur by chance, with a background rate of GBS of 2 per 100,000 per year. The same vaccine should be used to complete the vaccination course, as there is an increased rate of known side-effects if mixed schedules are used.
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